Case study
From years to weeks.
An API that had resisted crystallisation for more than four years – delivered for single-crystal X-ray in four weeks.
The challenge
Four years, and not one suitable crystal.
A leading pharmaceutical company faced a major roadblock – determining the structure of one of their active pharmaceutical ingredients. Multiple contract research organisations had spent, in total, more than four years trying to obtain single crystals suitable for single-crystal X-ray, without success. Then they turned to us.
What ELDICO did
Precision, speed, unmatched expertise.
Our know-how and skill in crystallisation let us turn a long-standing problem around in just four weeks of work.
Crystallised for SC-XRD
Crystallised the API into a form suitable for single-crystal X-ray experiments.
Structure & absolute configuration
Determined the structure, including absolute-configuration confirmation using synchrotron radiation.
Answered the problem
Provided a definitive answer to a question that had stood open for years.
The difference
4 years → 4 weeks
from an unsolved crystallisation problem to a confirmed structure.
Why work with ELDICO
When every moment counts.
We can deliver crystalline material on small molecules, including:
- Active pharmaceutical ingredients (APIs)
- Co-crystals and salts
- (Meta-stable) hydrates and solvates
- Specific polymorphic forms
- Natural products
Read the full case study.
See how four years of failed crystallisation became a confirmed structure in four weeks.
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