Applications

Where electron diffraction changes the answer.

Thirty days to grow a crystal for X-ray – or an electron-diffraction dataset in minutes, roughly a thousand times faster (febuxostat, CrystEngComm 2024). The solid-form questions electron diffraction answers, across pharma, agrochem, battery, biomaterials and materials.

Electron diffraction pattern appearing on the ED-1 control screen
Solved crystal structure – a pharmaceutical polymorph

Pharmaceutical solid-form ID

Polymorphs, salts, cocrystals and hydrates – resolved when the crystals are too small to grow for single-crystal X-ray.

Crystal structure from electron diffraction

Impurity & trace-phase analysis

Identify phases present below the powder-diffraction detection threshold, at the single-crystallite level.

Small-molecule crystal structure

Scarce & precious material

Complete structures from milligram-scale samples – early-stage APIs, precious batches and forensic amounts too small to crystallise for single-crystal X-ray.

Fine-chemical crystal structure

Agrochemicals & fine chemicals

Solid-form characterisation for compounds that resist conventional crystallography.

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By sector

Where electron diffraction delivers

Pharmaceuticals

Polymorphs, salts and co-crystals, absolute configuration and impurity identification – from milligram-scale samples.

Agrochemicals

Actives and formulations where crystals are too small or scarce for single-crystal X-ray.

Battery & energy materials

Cathode, electrolyte and other functional materials at the nanoscale.

Biomaterials

Peptides, small biomolecules and related structures.

Materials science

Catalysts, MOFs, pigments and fine chemicals.

From screening to certainty

One method, across the solid-form workflow.

Whether you're screening polymorphs, chasing a trace impurity, confirming absolute configuration or working from milligrams of a precious batch, electron diffraction returns a definitive structure – where powder methods stop at a fingerprint and single-crystal X-ray needs crystals you often can't grow.

Every area here is backed by worked examples in our library – real samples, real structures, with the data and reports behind them.

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Not sure it fits your sample?

A feasibility study answers that before any full measurement.

Discuss feasibility study